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sigma plot, version 5.0  (SPSS Inc)


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    SPSS Inc sigma plot, version 5.0
    Sigma Plot, Version 5.0, supplied by SPSS Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/sigma+plot+version+5%2E0/sigma+plot+software/pm11816009-193-6-9
    Average 90 stars, based on 1 article reviews
    sigma plot, version 5.0 - by Bioz Stars, 2026-10
    90/100 stars

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    Article Title: An integrated process for measuring the physicochemical properties of drug candidates in a preclinical discovery environment.
    Article Snippet: Automated log P, pKa, solubility, and chemical stability systems comprise an integrated process that provides early stage physicochemical property data to the discovery research organization.. Capillary electrophoresis (CE) techniques are used to experimentally determine pKa and log P. Solubility is determined using a quasiequilibrium approach employing sample quantitation by ̄ow injection analysis with ultraviolet (UV) detection at 256 nm.. Chemical stability is assessed by challenging compounds with pH 2, pH 7, pH 12, and 3% hydrogen peroxide solutions overnight, and comparing the chromatographic pro®les of the stability challenged solutions to that of a freshly prepared control.

    Article Title: A novel fluorescence assay to study propeptide interaction with gamma-glutamyl carboxylase.
    Article Snippet: The vitamin K-dependent gamma-glutamyl carboxylase catalyzes the posttranslational modification of select glutamate residues of its vitamin K-dependent substrates to gamma-carboxyglutamate.. In this report, we describe a new fluorescence assay that is sensitive and specific for the propeptide binding site of active carboxylase.. We employed the assay to make three important observations: (1) A tight binding fluorescein-labeled consensus propeptide can be used to quantify the active fraction of the enzyme. (2) The off-rate for a fluorescein-labeled factor IX propeptide was 3000-fold slower than the rate of carboxylation, a difference that may explain how carboxylase can carry out multiple carboxylations of a substrate during the same binding event. (3) We show evidence that substrate binding to the active site modifies the propeptide binding site of carboxylase.

    Article Title: Flow in hemodialysis grafts after angioplasty: Do radiologic criteria predict success?
    Article Snippet: Anastomotic or native version 2.03 and Sigma Plot version 5.0 (SPSS, Inc., Rich-vein stenoses producing greater than 50% diameter remond, CA, USA) were used for data analyses.duction were treated using standard angioplasty tech- niques [5].

    Article Title: Chronic exposure to ethanol alters GABA(A) receptor-mediated responses of layer II pyramidal cells in adult rat piriform cortex.
    Article Snippet: Signore, Armando P. and Hermes H. Yeh.. Chronic exposure to ethanol alters GABAA receptor-mediated responses of layer II pyramidal cells in adult rat piriform cortex.. J Neurophysiol 84: 247–254, 2000.



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